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Prof. Dr. Jan J.G.M. Verschuuren

Jan Verschuuren is a neurologist in the Department of Neurology at Leiden University Medical Center (LUMC), Leiden, Netherlands.  He received his medical training from the University of Maastricht, Netherlands (1979-1985). He completed his PhD thesis on experimental autoimmune myasthenia gravis (promoter prof.dr. P.J.C. van Breda Vriesman and co-promotor dr. M.H. De Baets; 1985-1989), and his neurology training at the University Hospital of Maastricht. He was a Research Fellow at the Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York (prof. J. Posner and dr. J. Dalmau 1994-1995). Since then he has been working as neurologist at the LUMC, with special focus on neuromuscular diseases.

His research projects focus on neuroimmunological diseases, like myasthenia gravis, Lambert-Eaton myasthenic syndrome, and inclusion body myositis. In close collaboration with dr. Jaap Plomp in vitro electrophysiology of the neuromuscular synaps is studied in animal models of myasthenia and inflammatory neuropathies, like the Miller-Fisher syndrome. In close collaboration with the department of human genetics (prof. dr. Gert Jan van Ommen) he is involved in research on therapies in Duchenne muscular dystrophy. He was the principal investigator of the first-in-man antisense oligonucleotide trial in 2006 in Duchenne muscular dystrophy. He is participating in European consortia and workshops on myasthenia gravis, paraneoplastic syndromes and Duchenne muscular dystrophy. Since January 2006 he is a member of the Dutch centre for research in neuromuscular disorders (ISNO).